Aerobic power and muscle strength of individuals living with HIV/AIDS.

AIM: We wished to evaluate any continuing adverse effects upon peak aerobic power and muscle strength associated with either HAART therapy or persistently low CD4⁺ counts in men living with HIV/AIDS. METHODS: We studied 39 HIV/AIDS patients with an average disease history of 6.1 years, and 28 normal sedentary volunteers. All subjects performed tests of peak aerobic power and isokinetic muscle force, and the HIV/AIDS group also completed the Profile of Mood States (POMS) and WHO Quality of Life questionnaires. Blood was sampled for standard measures of immune function (CD4⁺ and CD8⁺ counts) and viral load. RESULTS: Patient values were generally as in the normal subjects and appeared to be uninfluenced by the CD4+ nadir or the use of HAART therapy. However, the isokinetic muscle strength was lower in individuals with a low current CD4⁺ count. Isokinetic strength was also negatively correlated with current CD4⁺ and CD8⁺ counts. CONCLUSION: HAART therapy does not appear to have an adverse long-term effect on either aerobic power or muscle strength. Many ambulatory volunteers living with HIV/AIDS have a normal peak aerobic power. However, isokinetic strength can remain low, particularly in those with low current T-cell counts.

The association between Scoliosis Research Society-22 scores and scoliosis severity changes at a clinically relevant threshold.

STUDY DESIGN: Cross-sectional correlation study. OBJECTIVE: To determine the threshold in spinal deformity severity measurements beyond which there is a progressive decline in health-related quality-of-life (HRQOL). SUMMARY OF BACKGROUND DATA: The associations between HRQOL and scoliosis deformity measures are at best moderate when assessed using linear regressions. This may be because HRQOL is not affected until a severity threshold is reached. Identifying the thresholds in deformity beyond which HRQOL deteriorates could assist in treatment recommendations. METHODS: The Scoliosis Research Society-22 (SRS-22) questionnaire was completed by 101 females with adolescent idiopathic scoliosis (age, 15.0 +/- 1.8; largest Cobb angle, 36.9 degrees +/- 14.6 degrees). Radiographs and surface topography were used to quantify the severity of the internal (largest Cobb angle) and external deformity (cosmetic score, decompensation, trunk twist), respectively. Segmented linear regression models were estimated to determine the association between SRS-22 domains and spinal deformity measures. This analysis also identifies deformity thresholds beyond which HRQOL is more affected. The percentage of variance explained (R2) by linear and segmented models were compared (alpha = 0.05) to identify the best models. RESULTS: Cobb angle predicted significantly more variance in all SRS-22 domains except mental health using segmented models (R2: 0.09-0.30) than linear models (R2: 0.02-0.21). Segmented models with a single threshold estimated at a Cobb angle between 43 degrees and 48 degrees predicted between 3% and 11% more variance compared to corresponding linear model using the same variables. Surface topography parameters were not strongly associated with SRS-22 variables with linear and segmented models explaining less than 10% of the variance. CONCLUSION: Deterioration in SRS-22 scores is mildly associated with increases in the severity of the internal deformity. HRQOL is stable until the curve reaches a maximal Cobb angle threshold at approximately 45 degrees where HRQOL declines linearly with increasing internal deformity. The association between HRQOL and scoliosis severity is low, but is better explained by segmented rather than linear models.

Representation of bone heterogeneity in subject-specific finite element models for knee.

Properly representing the heterogeneous distribution of bone tissue material properties is a key step in constructing subject-specific finite element (FE) bone models from computed tomography (CT) data. Conventional methods represent heterogeneity by subjectively grouping bone of similar attenuation together. A new technique characterizing the level of heterogeneity with an objective metric is presented. This technique identifies the minimal level of heterogeneity needed for an accurate FE model. Subject-specific models of the distal femur and proximal tibia were used in this study. An innovative application of an image processing technique in the context of material properties modeling was introduced to facilitate an objective grouping strategy, which gathered together bone based not only on density but also on location thus capturing the natural variation of bone density seen in CT images. A fully heterogeneous model containing unique material properties for each finite element was not necessary to generate an appropriate solution. Von Mises stress, strain energy density, and nodal displacements were predicted within 5% accuracy using a simplified FE femur model containing less than half the number of bone groups of the fully heterogeneous model. Each group contained attenuations varying less than 20% from the group mean. A substantial computational time savings of 60% was gained with the application of the new technique to assign bone mechanical properties.

Characterizing torso shape deformity in scoliosis using structured splines models.

This paper describes a method of characterizing the torso shape deformity associated with scoliosis by both its type and severity. This problem is challenging because regular human torsos show an astounding range of variations that is only compounded by scoliosis, and it is difficult to isolate natural shape variations from those caused by scoliosis. Torso shape characterization is important in the clinical management of scoliosis because torso aesthetics is a key concern that influences a patient's quality of life. Our method involves modeling 3-D torso range images into structured sequences of 3-D spline curves stacked along the spine. We obtain local shape measures from points of maximal curvature (dominant points) along each torso cross section by evaluating the relative symmetry of the spline curve at that cross section. This results in a scalable characterization scheme for torso deformity type and a measure of torso deformity severity. We assess the accuracy and precision of this shape characterization scheme, and its relationship to the actual deformities present in the underlying spine.

Range data pre-processing for the evaluation of torso shape and symmetry in scoliosis.

Pre-processing range scans of the human torso for evaluating shape and symmetry changes in scoliosis are non-trivial. First, stray points from surrounding artefacts are often arbitrarily positioned and not amenable to automatic removal. Second, the asymmetrical alignment of the arms and neck makes cropping them difficult. Third, despite a plethora of methods, removal of holes by surface approximation for this niche application remains a challenge particularly in obscure regions like the sides and armpits. This paper proposes a novel surface approximation method and incorporates it into an integrated procedure for pre-processing range scans of the torso that includes interactive tools for cropping stray points and extremities. The new method, spline-fitted moving least squares (MLS), makes use of the Bezier curve and MLS algorithms. Numeric and clinical tests on scans of 30 volunteers, with and without scoliosis, show that the proposed method outperforms its constituent methods and a commercially available graphics package for this application.

A influência postural do salto alto em mulheres adultas: análise por biofotogrametria computadorizada / Postural influence of high heels among adult women: analysis by computerized photogrammetry

INTRODUÇÃO: Em nossa sociedade, temos observado uma oferta cada vez maior de modelos, cores, estilos, altura e diversos tipos de salto. OBJETIVO: Avaliar se o uso de calçados de salto alto influencia nas alterações posturais com base em um conjunto de variáveis mensuradas por meio da fotogrametria computadorizada. MÉTODOS: Vinte indivíduos que utilizam salto alto com freqüência (grupo 1) e 20 indivíduos que utilizam salto alto esporadicamente (grupo 2) foram fotografados no plano frontal anterior e sagital em três momentos: a) sem utilização de calçado, b) utilizando salto agulha e c) utilizando salto plataforma, sendo estas fotografias aleatorizadas e analisadas por um experimentador cego por meio da fotogrametria. A análise estatística foi realizada a partir da análise de variância em esquema fatorial 2x3, ou seja, comparando-se a freqüência do uso de salto com o tipo de calçado, com 5 por cento de significância. RESULTADOS: Apenas o ângulo protrusão da cabeça apresentou diferença quando comparados grupo 1 e 2 (p<0,01). O efeito do tipo de calçado ocorreu na variável alinhamento do joelho direito, sendo que houve diferença apenas entre o sapato agulha e os pés descalços (p=0,03); também para a variável ângulo tibiotársico, o efeito esteve presente em todos os tipos de calçado. Os demais ângulos avaliados não apresentaram diferenças entre a freqüência no uso de salto e os outros tipos de sapato. CONCLUSÕES: A freqüência do uso de salto e o tipo de salto praticamente não modificam a postura estática avaliada pela fotogrametria.

INTRODUCTION: In our society, it is observed an increasing number of models, colors, styles, heights and types of high heels. OBJECTIVE: To evaluate whether the use of high heel shoes results in postural changes, based on a set of variables measured through computerized photogrammetry. METHODS: Twenty individuals who often used high heels (group 1) and 20 individuals who only used high heels sporadically (group 2) were photographed in the frontal and sagittal planes at three conditions: a) without using footwear; b) using stiletto heels; and c) using high platform heels. These photographs were randomized and analyzed by a blinded examiner, by means of photogrammetry. Statistical analysis was performed, using a 2x3 factorial analysis of variance to compare the frequency of high heel use with the type of shoe, at the 5 percent significance level. RESULTS: Only the head protrusion angle showed a difference between groups 1 and 2 (p<0.01). The effect of the type of shoe observed in the alignment of the right knee, which only showed a difference between stiletto heels and barefoot (p=0.03). For the tibiotarsal angle variable, the effect was also observed for all types of footwear. The other angles evaluated did not present any differences regarding the frequency of high heel use and the types of shoe. CONCLUSIONS: The frequency and type of high heel practically did not change the static posture evaluated by photogrammetry.

Clinical monitoring of torso deformities in scoliosis using structured splines models.

This paper describes the use of structured splines indices for the clinical monitoring of torso deformity in scoliosis. Structured splines indices are computed from the distribution of points of maximal curvature (dominant points) of an object. The suitability and robustness of the indices for this application is assessed by ascertaining their robustness to inevitable torso shape variations due to sway and breathing and the variability in their values relative to existing clinical measures of deformity. To assess the consistency of these indices with other indices in use for this application, they were used to assess the relative information contents of the front and back of the torso. Results show that structured splines indices are more robust than existing clinical measures for monitoring torso deformity in scoliosis. Results also show that the scoliosis information content ratio of the back torso to the front torso is three to one.

A machine learning approach to assess changes in scoliosis.

This paper presents a machine learning approach that can be used to evaluate the validity of the results obtained with an automated system to measure changes in scoliotic curves. The automated system was used to measure the inclinations of 141 vertebral endplates in spine radiographs of patients with scoliosis. The resulting dataset was divided into training and test set. The training set was used to configure three classifiers: a support vector classifier (SVC), a decision tree classifier (DT) and a logistic regression classifier (LR). Their performance was evaluated on the test set. The SVC had an accuracy of 86% discriminating Good Results (those in which the error was less than 3 degrees ) from Bad Results. This accuracy was better than that of the LR (76%) and DT (68%). The differentiation between Good and Bad Results using the proposed machine learning approach was achieved successfully.

A NURBS-based technique for subject-specific construction of knee bone geometry.

Subject-specific finite element (FE) models of bones that form the knee joint require rapid and accurate geometry construction. The present study introduces a semi-automatic non-uniform rational B-spline (NURBS) technique to construct knee bone geometries from computed tomography (CT) images using a combination of edge extraction and CAD surface generation. In particular, this technique accurately constructs endosteal surfaces and can accommodate thin cortical bone by estimating the cortical thickness from well-defined surrounding bone. A procedure is also introduced to overcome the bifurcation at the femoral condyles during surface generation by combining transverse and sagittal plane CT data. Available voxel- and NURBS-based subject-specific construction techniques accurately capture periosteal surfaces but are limited in their ability to capture endosteal geometry. In this study, the proposed NURBS-based technique and a typical voxel mesh technique captured periosteal surfaces within an order of magnitude of image resolution. The endosteum of diaphyseal bone was also captured with similar accuracy by both techniques. However, the voxel mesh model failed to accurately capture the metaphyseal and epiphyseal endosteum due to the poor CT contrast of thin cortical bone, resulting in gross overestimation of cortical thickness. The proposed technique considered both the local and global nature of CT images to arrive at a description of cortical bone thickness accurate to within 2 pixel lengths.

A wireless personal wearable network system to understand the biomechanics of orthotic for the treatment of scoliosis.

The wear tightness of an orthosis for the treatment of scoliosis varies greatly during daily activities. Currently, there is no commercially available product that can monitor force distribution inside the brace and the time that the othosis is worn during daily activities. Subjective feeling is the most commonly used method. To provide an objective measure, a battery-powered wireless personal wearable network system is developed. This system consists of up to 16 wireless force loggers and a USB ZigBee dongle. Each logger contains a force sensor and a wireless unit. The whole system records how much time the orthosis has been used and how loads distribute inside the orthoses. Laboratory tests have been performed; the maximum force measurement error is +/-0.02N and the resolution is 0.1N. The average power consumption of the system is 0.3mW/h and thus a single AAA-sized alkaline battery is able to support the power for 6 months.

Validating an imaging and analysis system for assessing torso deformities.

We present the results of the numeric and functional validation of an imaging and analysis system used for assessing human torsos for deformities such as scoliosis. The system comprises of image acquisition, image reconstruction, and shape analysis components. The numeric validation procedure consists of assessing the accuracy of reconstruction of the system using inanimate models (a calibration box and a mannequin). The functional validation involves determining the system's response to variations in shape caused by sway and breathing, and evaluating the variability of a clinically relevant index, the Cosmetic Score, from multiple scans of scoliosis and non-scoliosis volunteers. Results show that the reconstruction accuracy of the system is 1.16+/-1.04 mm. This is better than the required accuracy for monitoring scoliosis of 2 mm. The system is robust to shape variations caused by sway and breathing and shows limited variability to the Cosmetic Score.

The effect of pulsed electromagnetic fields on chondrocyte morphology.

Osteoarthritis is a debilitating joint disease where the articular cartilage surface degrades and is unable to repair itself through natural processes. Chondrocytes reside within the cartilage matrix and maintain its structure. We conducted in vitro experiments to investigate the morphological response of cultured human chondrocytes under different pulsed electromagnetic field (PEMF) conditions. In the control experiments, cultured chondrocytes attached to the bottom of a culture dish typically displayed either a stellate or spindle morphology with extended processes. Experimental chondrocyte cultures were placed in a Helmholtz coil to which a ramp waveform was applied. Exposure to PEMFs caused the chondrocytes to retract their processes, becoming spherical in shape. This change in morphology followed a progression from stellate to spindle to spherical. These morphological changes were reflected in an average reduction of 30% in the surface contact area of the chondrocytes to the culture dish. Understanding the mechanisms by which PEMFs affect the morphology of chondrocytes will help lead to new treatments for osteoarthritis.

Contribution of loading conditions and material properties to stress shielding near the tibial component of total knee replacements.

This communication reports important preliminary results of a parametric analysis into the stress shielding effects of loading conditions and material properties of a total knee replacement (TKR) prosthesis. A previously developed finite element (FE) model of the proximal tibia that incorporated orthotropic and heterogeneous bone properties was used. Tibiofemoral joint compression and soft tissue (ligament and muscle) forces were also included to better represent the loading condition in the tibia. Stress shielding effects were studied for a prosthesis similar to a commercially available model. Results from the model show that the hypothesis of relatively higher Young's modulus of implant compared to bone as the primary cause of stress shielding is not sufficiently descriptive. Loading conditions as a result of altered bone or implant condylar surface geometry, load placement on the condylar surface, and load pattern created by the TKR are at least as important or, in some cases, more important factors in observed stress shielding immediately post-operation. This finding can be used to focus new implant design on altered loading conditions as well as material selection.

Impact of acute exposure to air pollution on the cardiorespiratory performance of military firemen.

The objective of the present study was to determine the impact of acute short-term exposure to air pollution on the cardiorespiratory performance of military firemen living and working in the city of Guarujá, São Paulo, Brazil. Twenty-five healthy non-smoking firemen aged 24 to 45 years had about 1 h of exposure to low and high levels of air pollution. The tests consisted of two phases: phase A, in Bertioga, a town with low levels of air pollution, and phase B, in Cubatão, a polluted town, with a 7-day interval between phases. The volunteers remained in the cities (Bertioga/Cubatão) only for the time required to perform the tests. Cumulative load 10 +/- 2 min-long exertion tests were performed on a treadmill, consisting of a 2-min stage at a load of 7 km/h, followed by increasing exertion of 1 km h-1 min-1 until the maximum individual limit. There were statistically significant differences (P < 0.05) in anaerobic threshold (AT) between Cubatão (35.04 +/- 4.91 mL kg-1 min-1) and Bertioga (36.98 +/- 5.62 mL kg-1 min-1; P = 0.01), in the heart rate at AT (AT HR; Cubatão 152.08 +/- 14.86 bpm, Bertioga 157.44 +/- 13.64 bpm; P = 0.001), and in percent maximal oxygen consumption at AT (AT%VO2max; Cubatão 64.56 +/- 6.55%, Bertioga 67.40 +/- 5.35%; P = 0.03). However, there were no differences in VO2max, maximal heart rate or velocity at AT (ATvel) observed in firemen between towns. The acute exposure to pollutants in Cubatão, SP, caused a significant reduction in the performance at submaximal levels of physical exertion.

Confiabilidade inter e intra-examinador da fotopodometria e intra-examinador da fotopodoscopia / Inter and intra-examiner reliability of photopodometry and intra-examiner reliability of photopodoscopy

OBJETIVO: O propósito deste estudo foi avaliar a confiabilidade inter e intra-examinador da fotopodometria, bem como a confiabilidade intra-examinador da fotopodoscopia. MÉTODO: Foram fotografadas as impressões plantares de 30 indivíduos hígidos de ambos os sexos, com idade média de 21,0 ±1,32 anos, posicionados sobre um podoscópio, com os pés descalços, apoio bipodal e postura ortostática. A imagem da impressão plantar refletida no vidro desse aparelho foi capturada por meio de uma câmera fotográfica digital de 2.1 megapixels, posicionada sobre um tripé em frente ao mesmo. As imagens foram arquivadas e, em seguida, submetidas às análises inter e intra-examinador. Para verificar a confiabilidade intra-examinador da fotopodoscopia, após quatro semanas, toda a metodologia de captura e análise de novos podogramas dos mesmos indivíduos foi repetida. RESULTADOS: As análises inter e intra-examinador da fotopodometria apresentaram, respectivamente, ICC= 0,96 e ICC= 0,98. O ICC de confiabilidade intra-examinador da fotopodoscopia foi de 0,94. CONCLUSÃO: Conclui-se então que a fotopodometria é um recurso de análise quantitativa confiável, sendo também a fotopodoscopia um método de avaliação aplicável para análises clínicas e científicas, permitindo, assim, acompanhar a evolução de tratamentos fisioterapêuticos dos apoios plantares, mesmo levando-se em consideração as variabilidades intrínsecas e extrínsecas dos indivíduos.

OBJECTIVE: To evaluate the inter and intra-examiner reliability of photopodometry and the intra-examiner reliability of photopodoscopy. METHOD: Plantar prints from 30 healthy individuals of both sexes with mean age of 21.0 ± 1.32 years were photographed. These individuals were positioned on a podoscope with bare feet, bipedal support and orthostatic posture. The plantar print images reflected on the glass of this instrument were captured using a 2.1 megapixel digital photographic camera positioned on a tripod in front of the podoscope. The images were filed and subsequently subjected to inter and intra-examiner analysis. To verify the intra-examiner reliability of photopodoscopy, the whole procedure of podogram capture and analysis was repeated on the same individuals four weeks later. RESULTS: The intraclass correlation coefficients (ICC) for the inter and intra-examiner analyses on the photopodometry were, respectively, 0.96 and 0.98. The ICC for the intra-examiner reliability of the photopodometry was 0.94. CONCLUSION: Photopodometry is a reliable quantitative analysis method and photopodoscopy is an evaluation method applicable to clinical and scientific analyses. They therefore make it possible to follow up the evolution of physiotherapeutic treatment on plantar supports, despite the intrinsic and extrinsic variability between individuals.

Impact of acute exposure to air pollution on the cardiorespiratory performance of military firemen

The objective of the present study was to determine the impact of acute short-term exposure to air pollution on the cardiorespiratory performance of military fireman living and working in the city of Guarujá, São Paulo, Brazil. Twenty-five healthy non-smoking firemen aged 24 to 45 years had about 1 h of exposure to low and high levels of air pollution. The tests consisted of two phases: phase A, in Bertioga, a town with low levels of air pollution, and phase B, in Cubatão, a polluted town, with a 7-day interval between phases. The volunteers remained in the cities (Bertioga/Cubatão) only for the time required to perform the tests. Cumulative load 10 ± 2 min-long exertion tests were performed on a treadmill, consisting of a 2-min stage at a load of 7 km/h, followed by increasing exertion of 1 km h-1 min-1 until the maximum individual limit. There were statistically significant differences (P < 0.05) in anaerobic threshold (AT) between Cubatão (35.04 ± 4.91 mL kg-1 min-1) and Bertioga (36.98 ± 5.62 mL kg-1 min-1; P = 0.01), in the heart rate at AT (AT HR; Cubatão 152.08 ± 14.86 bpm, Bertioga 157.44 ± 13.64 bpm; P = 0.001), and in percent maximal oxygen consumption at AT (AT percentVO2max; Cubatão 64.56 ± 6.55 percent, Bertioga 67.40 ± 5.35 percent; P = 0.03). However, there were no differences in VO2max, maximal heart rate or velocity at AT (ATvel) observed in firemen between towns. The acute exposure to pollutants in Cubatão, SP, caused a significant reduction in the performance at submaximal levels of physical exertion.

Automatic matching of spine images to assess changes in scoliosis.

This paper presents an image matching approach that can be used to measure changes in scoliotic curves. The proposed approach uses a novel fuzzy logic controller to estimate all open parameters. Using fluoroscopy images of a spine phantom, it was found that, with minimal user interaction, the matching of spine images could be achieved with high accuracy (the average errors were around 0.03 mm) and high computational efficiency (requiring less than 1 minute for matching each vertebra).

Intra-operative spinal load and displacement monitoring: towards a better understanding of scoliosis correction mechanics.

Surgical correction of scoliosis reduces deformation and improves overall function and esthetics. Understanding and monitoring of mechanics during scoliosis surgery is an invaluable tool to optimize correction without compromising patient safety. Our objective was to use intra-operative monitoring tools to study how spinal load and displacement relates to obtained correction and chosen instrumentation. Instrumented pedicle screws, a "gripper" and active markers were developed. Instrumented pedicle screws provided three-dimensional forces at the screw-vertebra interface while the instrumented "gripper" measured the force and the rotation applied by the surgeon to the rod rotator. Vertebral displacement was monitored with light-emitting diodes and motion capture technology. These instruments were used successfully with 16 scoliosis subjects. Analysis of applied force, displacement, and curve flexibility influence on correction percentage is the long term goal. Raw results for instrumented screws and gripper showed that recorded force decreased with respect to percentage of correction obtained. Measured force increased with respect to the pre-surgical Cobb angle while percentage of correction obtained decreased as pre-surgical Cobb angle increased. Active marker results showed three-dimensional vertebral rotation and translation during correction, with axial rotation and caudal-cranial translation having the greatest magnitudes. Using greater correction forces does not necessarily result in an increased correction; flexibility and Cobb angle also play a role in the mechanics of correction. Further data collection will provide better understanding of the interconnected role between these factors helping complete the description of surgery mechanics.

Evaluating similarity metrics in an image matching tool for image guided spine surgery.

This paper presents a comparison study of the effect of three similarity measures (mutual information, normalized mutual information, and mean squared error on the edges of the input image) in an image matching tool that can be used in image guided spine surgery. Using 3D rotational x-rays and magnetic resonance images of a spine phantom, it was found that the similarity measures had similar effect. Therefore, experiments with other datasets are needed before making conclusions about the suitability of these similarity metrics for image guided surgery.

Os efeitos do ultra-som terapeutico nas lesões por esmagamento do nervo ciatico de ratos: analise funcional da marcha / Effects of therapeutic ultrasound on injuries due to crushing of the sciatic nerve in rats: functional evaluation of gait

Os efeitos da irradiacao ultra-sonica teraputica na regeneracao de nervos perifericos nao sao ainda bem conhecidos, particularmente no que se refere a recupercao funcional. Por outro lado o metodo da avaliacao da impressao da pegada do rato para medida do Indice Funcional do ciatico (IFC) ja esta bem sistematizado, mostrando streita correlacao com a regeneracao do nervo ciatico de ratos submetido a esmagamento ontrolado. Material e metodos: foram empregados 20 ratos da linhagem Wistar com peso corporal medio de 300g, divididos em dois grupos conforme o tipo de procedimento realizado: 1) somente esmagamento (n=10); 2)esmagamento e irradiacao com ultra-som (n=10). Sob anestesia geral, o nervo ciatico era exposto na coxa direita do animal e esmagado com um dispositivo especialmente confeccionado para essa finalidade, com uma carga fixa de 15 kg por 10minutos, num segmento de 5 mm proximal a sua bifurcacao. A irradiacao ultra-sonica pulsada de baixa intensidade (1:5, 0,4w/cm2, 1 MHz, duracao 2 minutos) era iniciada ja no rpimeiro dia pos-operatorio e realizada por dez dias consecutivos. As impressoes das pegadas dos animais, obtidas semanalmente, da primeira a terceira semana pos-operatoria em passarela especifica para essa finalidade, foram avaliadas por meio de um programa de computador igualmente especifico, segundo meto pre-existente ja testado em trabalhos anteriores, com calculo automatico do IFC. Resultados: o IFC aumentou progressivamente nos dois grupos, passando no Grupo 2 de 101 na primeira semana, para 59,21 na segunda e 26,68 na terceira, o que significou uma melhora de 73 por cento entre a primeira e a ultima medida. No grupo 1, o IFC subiu de -98,2 na primeira semana para -79,5 na segunda e -44 na terceira, o que significa uma melhora de 55 por cento entre a primeira medida e a ultima. As diferencas entre os grupos foram significativas no 14o. dia e no 21o. dia (p=0,02 e p=0,02, respectivamente). Conclusao: o ultra-som terapeutico de baixa intensidade acelerou a regeneracao do nervo ciatico do rato, demonstravel com maior significancia no 21o. dia pos-operatorio